[Influenza vaccination and mortality in the elderly].
Identifieur interne : 000613 ( Main/Exploration ); précédent : 000612; suivant : 000614[Influenza vaccination and mortality in the elderly].
Auteurs : Angel Vila-C Rcoles [Espagne] ; Olga Ochoa-Gondar ; Xabier Ansa-Echeverría ; Albert G Mez-Sorribes ; Pilar Espelt-Aluja ; Ignacio Pascual-Mor NSource :
- Medicina clinica [ 0025-7753 ] ; 2005.
Descripteurs français
- KwdFr :
- MESH :
- administration et posologie : Vaccins antigrippaux.
- statistiques et données numériques : Vaccination.
- épidémiologie : Espagne.
- Femelle, Humains, Modèles logistiques, Mortalité, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Études de cohortes.
- Wicri :
- geographic : Espagne.
English descriptors
- KwdEn :
- MESH :
- chemical , administration & dosage : Influenza Vaccines.
- geographic , epidemiology : Spain.
- statistics & numerical data : Vaccination.
- Aged, Aged, 80 and over, Cohort Studies, Female, Humans, Logistic Models, Male, Mortality.
Abstract
BACKGROUND AND OBJECTIVE
Though there is a general agreement on the need of influenza vaccination (IV), very different results have been published about the magnitude of its effect. We evaluated the effectiveness of IV in the reduction of mortality in individuals over 65 years of age.
PATIENTS AND METHOD
Prospective cohort study of all individuals over 65 attended in 8 urban primary care centers (n = 11,241). We assessed IV in autumn 2001 and considered the death from all causes during 2002 as a response variable. We calculated the global effectiveness (1-relative risk) and the necessary number of vaccinations in order to prevent 1 death (NNT = 1/attributable risk).
RESULTS
Global effectiveness of IV was 2%, considering an NNT of 1667. No vaccination benefit among the 65-74 years-old group was observed, but IV proved 22% effectiveness (95% confidence interval, 3-38%) in individuals over 75, with an estimated NNT of 66 vaccinations (95% confidence interval, 38-435).
CONCLUSIONS
Within a year with a moderate incidence of influenza, IV had a small effectiveness in preventing general mortality in our area, though it was especially effective among those at higher risk (over 75 and suffering from chronic pathologies).
DOI: 10.1016/s0025-7753(05)72156-4
PubMed: 16324480
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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last="Ansa-Echeverría">Xabier Ansa-Echeverría</name></author><author><name sortKey="G Mez Sorribes, Albert" sort="G Mez Sorribes, Albert" uniqKey="G Mez Sorribes A" first="Albert" last="G Mez-Sorribes">Albert G Mez-Sorribes</name></author><author><name sortKey="Espelt Aluja, Pilar" sort="Espelt Aluja, Pilar" uniqKey="Espelt Aluja P" first="Pilar" last="Espelt-Aluja">Pilar Espelt-Aluja</name></author><author><name sortKey="Pascual Mor N, Ignacio" sort="Pascual Mor N, Ignacio" uniqKey="Pascual Mor N I" first="Ignacio" last="Pascual-Mor N">Ignacio Pascual-Mor N</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2005">2005</date><idno type="RBID">pubmed:16324480</idno><idno type="pmid">16324480</idno><idno type="doi">10.1016/s0025-7753(05)72156-4</idno><idno type="wicri:Area/Main/Corpus">00611</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">00611</idno><idno 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last="Ochoa-Gondar">Olga Ochoa-Gondar</name></author><author><name sortKey="Ansa Echeverria, Xabier" sort="Ansa Echeverria, Xabier" uniqKey="Ansa Echeverria X" first="Xabier" last="Ansa-Echeverría">Xabier Ansa-Echeverría</name></author><author><name sortKey="G Mez Sorribes, Albert" sort="G Mez Sorribes, Albert" uniqKey="G Mez Sorribes A" first="Albert" last="G Mez-Sorribes">Albert G Mez-Sorribes</name></author><author><name sortKey="Espelt Aluja, Pilar" sort="Espelt Aluja, Pilar" uniqKey="Espelt Aluja P" first="Pilar" last="Espelt-Aluja">Pilar Espelt-Aluja</name></author><author><name sortKey="Pascual Mor N, Ignacio" sort="Pascual Mor N, Ignacio" uniqKey="Pascual Mor N I" first="Ignacio" last="Pascual-Mor N">Ignacio Pascual-Mor N</name></author></analytic><series><title level="j">Medicina clinica</title><idno type="ISSN">0025-7753</idno><imprint><date when="2005" type="published">2005</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>Cohort Studies (MeSH)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Influenza Vaccines (administration & dosage)</term><term>Logistic Models (MeSH)</term><term>Male (MeSH)</term><term>Mortality (MeSH)</term><term>Spain (epidemiology)</term><term>Vaccination (statistics & numerical data)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Espagne (épidémiologie)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Modèles logistiques (MeSH)</term><term>Mortalité (MeSH)</term><term>Mâle (MeSH)</term><term>Sujet âgé (MeSH)</term><term>Sujet âgé de 80 ans ou plus (MeSH)</term><term>Vaccination (statistiques et données numériques)</term><term>Vaccins antigrippaux (administration et posologie)</term><term>Études de cohortes (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Influenza Vaccines</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Spain</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Vaccins antigrippaux</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Vaccination</term></keywords><keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Vaccination</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Espagne</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Cohort Studies</term><term>Female</term><term>Humans</term><term>Logistic Models</term><term>Male</term><term>Mortality</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Femelle</term><term>Humains</term><term>Modèles logistiques</term><term>Mortalité</term><term>Mâle</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Études de cohortes</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Espagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND AND OBJECTIVE</b></p><p>Though there is a general agreement on the need of influenza vaccination (IV), very different results have been published about the magnitude of its effect. We evaluated the effectiveness of IV in the reduction of mortality in individuals over 65 years of age.</p></div><div type="abstract" xml:lang="en"><p><b>PATIENTS AND METHOD</b></p><p>Prospective cohort study of all individuals over 65 attended in 8 urban primary care centers (n = 11,241). We assessed IV in autumn 2001 and considered the death from all causes during 2002 as a response variable. We calculated the global effectiveness (1-relative risk) and the necessary number of vaccinations in order to prevent 1 death (NNT = 1/attributable risk).</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Global effectiveness of IV was 2%, considering an NNT of 1667. No vaccination benefit among the 65-74 years-old group was observed, but IV proved 22% effectiveness (95% confidence interval, 3-38%) in individuals over 75, with an estimated NNT of 66 vaccinations (95% confidence interval, 38-435).</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>Within a year with a moderate incidence of influenza, IV had a small effectiveness in preventing general mortality in our area, though it was especially effective among those at higher risk (over 75 and suffering from chronic pathologies).</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">16324480</PMID><DateCompleted><Year>2006</Year><Month>01</Month><Day>31</Day></DateCompleted><DateRevised><Year>2019</Year><Month>08</Month><Day>23</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0025-7753</ISSN><JournalIssue CitedMedium="Print"><Volume>125</Volume><Issue>18</Issue><PubDate><Year>2005</Year><Month>Nov</Month><Day>19</Day></PubDate></JournalIssue><Title>Medicina clinica</Title><ISOAbbreviation>Med Clin (Barc)</ISOAbbreviation></Journal><ArticleTitle>[Influenza vaccination and mortality in the elderly].</ArticleTitle><Pagination><MedlinePgn>689-91</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND AND OBJECTIVE" NlmCategory="OBJECTIVE">Though there is a general agreement on the need of influenza vaccination (IV), very different results have been published about the magnitude of its effect. We evaluated the effectiveness of IV in the reduction of mortality in individuals over 65 years of age.</AbstractText><AbstractText Label="PATIENTS AND METHOD" NlmCategory="METHODS">Prospective cohort study of all individuals over 65 attended in 8 urban primary care centers (n = 11,241). We assessed IV in autumn 2001 and considered the death from all causes during 2002 as a response variable. We calculated the global effectiveness (1-relative risk) and the necessary number of vaccinations in order to prevent 1 death (NNT = 1/attributable risk).</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Global effectiveness of IV was 2%, considering an NNT of 1667. No vaccination benefit among the 65-74 years-old group was observed, but IV proved 22% effectiveness (95% confidence interval, 3-38%) in individuals over 75, with an estimated NNT of 66 vaccinations (95% confidence interval, 38-435).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Within a year with a moderate incidence of influenza, IV had a small effectiveness in preventing general mortality in our area, though it was especially effective among those at higher risk (over 75 and suffering from chronic pathologies).</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Vila-Córcoles</LastName><ForeName>Angel</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Servicio de Atención Primaria de Tarragona-Valls, Institut Català de la Salut, Tarragona, Spain. avila.tarte.ics@gencat.net</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ochoa-Gondar</LastName><ForeName>Olga</ForeName><Initials>O</Initials></Author><Author ValidYN="Y"><LastName>Ansa-Echeverría</LastName><ForeName>Xabier</ForeName><Initials>X</Initials></Author><Author ValidYN="Y"><LastName>Gómez-Sorribes</LastName><ForeName>Albert</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Espelt-Aluja</LastName><ForeName>Pilar</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Pascual-Morón</LastName><ForeName>Ignacio</ForeName><Initials>I</Initials></Author></AuthorList><Language>spa</Language><PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><VernacularTitle>Vacunación antigripal y mortalidad general en población mayor de 65 años.</VernacularTitle></Article><MedlineJournalInfo><Country>Spain</Country><MedlineTA>Med Clin 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Echeverria, Xabier" uniqKey="Ansa Echeverria X" first="Xabier" last="Ansa-Echeverría">Xabier Ansa-Echeverría</name><name sortKey="Espelt Aluja, Pilar" sort="Espelt Aluja, Pilar" uniqKey="Espelt Aluja P" first="Pilar" last="Espelt-Aluja">Pilar Espelt-Aluja</name><name sortKey="G Mez Sorribes, Albert" sort="G Mez Sorribes, Albert" uniqKey="G Mez Sorribes A" first="Albert" last="G Mez-Sorribes">Albert G Mez-Sorribes</name><name sortKey="Ochoa Gondar, Olga" sort="Ochoa Gondar, Olga" uniqKey="Ochoa Gondar O" first="Olga" last="Ochoa-Gondar">Olga Ochoa-Gondar</name><name sortKey="Pascual Mor N, Ignacio" sort="Pascual Mor N, Ignacio" uniqKey="Pascual Mor N I" first="Ignacio" last="Pascual-Mor N">Ignacio Pascual-Mor N</name></noCountry><country name="Espagne"><noRegion><name sortKey="Vila C Rcoles, Angel" sort="Vila C Rcoles, Angel" uniqKey="Vila C Rcoles A" first="Angel" last="Vila-C Rcoles">Angel Vila-C Rcoles</name></noRegion></country></tree></affiliations></record>Pour manipuler ce 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